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NRC inks deal for cancer diagnostics

By: Lisa Williams, senior writer, InterGovWorld(08/17/06)

A developing technology could soon help detect lung cancer in its earliest stages.

Perceptronix Medical Inc. has signed a contribution agreement with the National Research Council Canada (NRC) in support of their ClearVu Elite advanced fluorescence bronchoscopy system.

Vancouver-based Perceptronix is a private cancer diagnostics company, a spin off of the B.C. Cancer agency.

The $95,000 in funding is being provided by the NRC's Industrial Research Assistance Program, which works with Canadian SMEs to provide a variety of technical and business focused advisory services and financial support.

The money from the NRC will cover the local Perceptronix researchers who are conducting data analysis and modeling for clinical trials, according to David Garner, vice-president and CSO, Perceptronix.

A bronchoscopy is a procedure in which a cylindrical fiberoptic scope is inserted into the airways. The scope contains a viewing device that allows the visual examination of the lower airways. Fluorescence bronchoscopy uses fluorescent light in the bronchoscope to detect precancerous cells.

The procedure has been around for about 15 years, Garner said.

"It was actually invented by the B.C. Cancer Agency," he said. "It's used for lung cancer detection, for the very early or pre-invasive stage -- you don't need it for more advanced lung cancer than that."

If successful it is technology that is sorely needed because current technologies only detect the cancer when the morbidity is high 80 per cent, according to Christopher Ryan, NRC-IRAP's pacific region executive director.

"Detection of lung cancer is problematic," said Ryan. "(Perceptronix) hopes to lower the detection threshold considerably thus increasing the chances of effective treatment."

According to Health Canada an estimated 153,100 new cases of cancer and 70,400 deaths from cancer will occur in Canada in 2006. The leading cause of cancer death for both sexes continues to be lung cancer.

Garner said that the technology is still in the development stage and is now in the equivalent of a phase two clinical study or trial.

"We're at the stage of really proving that it works," he said.

Garner estimated the trial will be completed by the end of the year, and that the system should hit the market in about two years.

Ryan said that successful completion and commercialization by Perceptronix could potentially be a great success story.

"It would have a great health impact in Canada and also globally," he said. "The potential success is one of the reasons the NRC supported this project."


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